Pharmaceutical drug discovery and development has been suffering from declining success rates with new molecules primarily because of poor external validity of preclinical models and lack of efficacy of the molecule in terms of the intended disease indication. Drug success rates continue to be in the range of only 1 in 10 that enters clinical phases pushing through to FDA approval. Frost & Sullivan finds that traditional solutions focused primarily on data from limited sources and rule-based computational techniques used to address the understanding of targets and leads are inefficient.
Artificial intelligence (AI) is set to transform the drug discovery landscape. AI-based products and solutions are transforming drug discovery and development dynamics by enabling pharmaceutical players to shorten discovery timelines, enhance process agility, increase prediction accuracy on efficacy and safety, and improve the opportunity to diversify drug pipelines using a cost-effective model.
Most pharmaceutical vendors are focused on collecting, creating, and augmenting data from across laboratories, clinical trials, real-world evidence, biobanks, and repositories. The increasing volume and veracity of clinical and research data is compelling traditional providers to leverage enabling tools and technologies such as cloud computing, AI and machine learning, natural language processing, and advanced analytics to make a shift to a relatively fast, rational data-driven drug discovery and development approach.
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